Biostimulators Sculptra vs Radiesse

Biostimulators: Sculptra vs Radiesse

Sculptra and Radiesse are both injectable “biostimulators.” They differ from traditional fillers because they stimulate or trigger your own body to make its OWN collagen!  Used for cosmetic purposes, but they have some differences in terms of their composition, intended uses, and longevity…read on…


  • Composition: Sculptra is made from poly-L-lactic acid, which is a biocompatible synthetic material. It is similar in structure to dissolvable suture material. Which has been used in surgical procedures for many years. (If you have ever had surgery and they didn’t need to remove your sutures you know what I’m talking about.) Over time, it breaks down naturally into lactic acid, CO2 and water.
  • Treatment Areas: Sculptra is primarily used to stimulate collagen production by stimulating the skin fibroblast cells and add volume to the face. It is often used for treating deep wrinkles, nasolabial folds, marionette lines, and sunken cheeks. It’s also used to restore volume loss in areas affected by fat atrophy.
  • Results: Sculptra doesn’t provide immediate results. It works by gradually stimulating collagen production in the treated areas, so the full effects become visible over several months. Typically 2-3 treatment session are needed spaced about 6-10 weeks apart. Typically 2 vials of Sculptra are needed each treatment.  Results can last up to two years or more. For best results we recommend maintenance treatments once a year with 1-2 vials to maintain results.


  • Composition: Radiesse is made from calcium hydroxylapatite microspheres suspended in a gel carrier. It is also considered biocompatible and breaks down into calcium and phosphate ions.
  • Treatment Areas: Radiesse is primarily used to add volume to areas of the face, such as nasolabial folds, marionette lines, and cheeks. It can also be used for hand rejuvenation.
  • Results: Radiesse provides immediate results because of the gel component which works as a filler, adding volume instantly. It also stimulates collagen and elastin production over time, which can extend the duration of results. The effects can last around 12 months.
  • Number of Sessions: Most patients achieve their desired results with one treatment session, however maintenance are typically required every 6-9 months and multiple sessions may be necessary to achieve desired results.

Key Differences:

  • Composition: Sculptra is made of poly-L-lactic acid, while Radiesse is composed of calcium hydroxylapatite microspheres. This difference in composition can influence how they interact with the body and the longevity of their effects.
  • Results: Sculptra provides a more gradual onset of results, while Radiesse offers immediate volume enhancement. The duration of results varies, with Sculptra typically lasting longer.
  • Treatment Plan: Sculptra usually requires multiple sessions to achieve optimal results, while Radiesse often requires fewer treatment sessions.
  • Areas of Use: Both products can be used for similar facial areas, but Sculptra is more commonly used for overall facial volumization, while Radiesse may be favored for specific lines and wrinkles.

The choice between Sculptra and Radiesse should be made with a thorough consultation with a medical professional, taking into consideration your specific cosmetic goals and preferences. We can assess your individual needs and recommend the most suitable option for you.

To schedule a consultation with us to discuss whether Sculptra or Radiesse is right for you click here.

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Alex grew up in Wisconsin and moved to Florida in 2016 to attend Florida Gulf Coast University. After graduating in 2020, she attended the University of Miami and received her Masters in Skin Biology. Alex has the long term goal of becoming a PA.

Jordan is another Naples, Florida homegrown! She comes to us with over 8 years of experience, previously specializing in vascular care. Jordan is also a busy mom of THREE boys, who finds her role of MOM as a source of inspiration and joy that fuels her commitment to making a positive impact professionally.

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Sharon is originally from the Boston area and has lived in Southwest Florida for over 20 years. Sharon came to us with 20 plus years of management and customer service experience. After staying at home to raise her twins for seven years she was excited to get back to work joining D-Lux Medspa in 2017. when she’s not working she enjoys cooking, gardening and has a passion for all things organization! Sharon and her husband Wayde also enjoy fishing trips, going diving with there children Carly and Chase or just going for a walk with their dog Ginger.

Alexis is a Naples Florida native who graduated from Florida Gulf Coast University in 2019. Alexis brings her organizational skills along with her experience in the field of aesthetic management. When she’s not busy getting things ship-shape at DLux, you’ll find her soaking up the sun at the beach, enjoying boat trips, traveling and spending quality time with her adorable son Landon and two furry companions, Beau and Riley.

Nichole moved to SouthWest Florida 10 years ago after residing in Albuquerque New Mexico for most of her life. She met Dana not long after her arrival and they have been fast friends ever since. With a background in sales and graphic design Nichole brings her passion for delivering impeccable customer/patient service to her role at Dlux Medspa. When she’s not at the office she enjoys cooking (ask her about her old food blog!), being “artsy” and helping curate the Dlux Instagram accounts. She tries to avoid exercise at any cost, but somehow manages to get a work out in every once in a while, even if it is against her will.